Job Description

Working with Us Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

At Bristol Myers Squibb we are reimagining the future of cell therapy. With our bold ambition, backed by a best-in-the-industry team and long-term commitment, we are leading the way to unlock the full promise of cell therapy as we strive to put more patients on the path to a cure. If you are ready to challenge yourself, accelerate your career, and give new hope to patients, theres no better place than here at BMS with our Cell Therapy team.

Position Summary

As a Principal Scientist with Cell Therapy Analytical Development, this energetic, collaborative, and motivated individual will establish and lead Non-Viral Attribute Science. This person will be responsible for the creation of a holistic analytical toolbox used to interrogate and discover quality attributes of non-viral gene editing drug substances including Ribonucleoprotein complexes, RNA species, and LNPs. Importantly, they will also assess attribute impact on downstream edited cell function. This position will help establish core expertise and knowledge within CTAD to support next generation cell therapy modalities.

Key Responsibilities

• Hands on development of robust analytical methods to support internal process development of non-viral materials, and their use thereof in cells
• Provide technical and scientific subject matter expertise to drive early non-viral development strategies
• Assist in the assessment of the analytical readiness of CDMO/CROs
• Identify and define Critical Quality Attributes (CQA) of non-viral drug substances
• Identify key measures of drug substance function in primary and immortal cells
• Contribute to the authorship of SOPs, technical reports and regulatory submission documents (including S.3.1 sections)
• Present and discuss findings to stakeholders and senior leadership
• Collaborate cross-functionally with CTAD peers, research, process development and CMC to support early platform assessment efforts

Qualifications & Experience

• Ph.D. in Immunology, Cell/Molecular Biology, Analytical Chemistry, Biomedical Engineering or related discipline with demonstrated track/record of experience leading teams to achieve objectives in industrial and/or academic settings (5+ years for Ph.D)
• Profound understanding of RNA and RNP biology especially in cell therapy applications
• Experience characterizing function of RNA and RNP reagents in primary cells (primary cell culture, gene expression by flow or molecular readout, potency and other functional assays)
• Familiarity with analytical methods used to characterize non-viral drug substances (ion exchange chromatography, size exclusion chromatography, icIEF, FRET, protein and nucleic acid quantitation, peptide mapping)
• Handson experience working with a non-viral gene delivery platform
• Experience with automation and high throughput analytical solutions is desired
• Motivation and drive to acquire new skills and knowledge
• Willingness to work in a regulated industrial environment
• Excellent verbal, written, and oral communication skills

If you come across a role that intrigues you but doesnt perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview

Seattle - WA: $144,440 - $175,028. The starting compensation range(s) for this role are listed above for a fulltime employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employees work schedule, jobrelated knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care; Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP); Financial wellbeing resources and a 401(K); Financial protection benefits such as short and longterm disability, life insurance, supplemental health insurance, business travel protection and survivor support; Worklife programs including paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Years holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility; Parental, caregiver, bereavement, and military leave; Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources; Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Lifechanging Careers

With a single vision as inspiring as Transforming patients lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Onsite Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes siteessential, sitebydesign, fieldbased and remotebydesign jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Siteessential roles require 100% of shifts onsite at your assigned facility. Sitebydesign roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For fieldbased and remotebydesign roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Accessibility & Accommodation

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Health & Safety

BMS cares about your wellbeing and the wellbeing of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit to find important additional information.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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